Anti E Igg Antibody

Description: Immunoglobulin G (IgG) is a monomeric immunoglobulin, built of two heavy chains and two light chains. Each IgG has two antigen binding sites. It is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75 % of serum immunoglobulins in humans. There are four IgG subclasses (IgG1, 2, 3 and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant).

Description: Immunoglobulin G (IgG) is a monomeric immunoglobulin, built of two heavy chains and two light chains. Each IgG has two antigen binding sites. It is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75 % of serum immunoglobulins in humans. There are four IgG subclasses (IgG1, 2, 3 and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant).

Description: Rabbit Polyclonal Antibody for Cathepsin E Antibody (CTSE) detection.tested for WB in Human, Mouse, Rat.

Description: HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

Description: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.

Description: Rabbit polyclonal to Arylsulfatase E.

Description: Rabbit polyclonal to Cathepsin E.

Description: Rabbit polyclonal to E-cadherin.

Description: E-cadherin is a protein encoded by the CDH1 gene which is approximately 97,4 kDa. E-cadherin is localised to the cell membrane and Golgi apparatus. It is involved in cell junction organization, ERK signalling and apoptotic cleavage of cellular proteins. It is a calcium-dependent cell-cell adhesion protein that is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells and has a potent invasive suppressor role. It is also a ligand for integrin alpha-E/beta-7. E-cadherin is expressed in non-neural epithelial tissues. Mutations in the CDH1 gene may result in endometrial cancer and breast cancer. STJ92819 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of E-cadherin protein.

Description: Rabbit polyclonal to E-Ras.